DHT Blocker
DHT Blocker
DHT Blocker
DHT Blocker
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DHT Blocker

DHT Blocker

Regular price
₹850.00
Sale price
₹850.00
Regular price
Sold out
Unit price
per 
FME.3.4
20.Feb.2024
20.Feb.2025

SUGGESTED USE

Adults take 1 capsule post lunch & 1 capsule post dinner daily, with a glass of water.

Nutrition Facts

Certificate of Analysis

Product Information

Unived's DHT Blocker, is designed to address the underlying cause of hair loss by combatting the damaging effects of DHT. Derived from testosterone, DHT binds to hair follicles and leads to their shrinking, resulting in thinning and eventual hair loss. Our supplement harnesses the power of natural DHT blockers which inhibit the production or activity of DHT, protecting the follicles and promoting optimal hair health and regrowth. With a blend of carefully selected ingredients working synergistically, Unived's DHT Blocker offers a holistic approach to restoring hair health and creating a supportive environment for hair growth and restoration.

Key Benefits

  • Helps to reduce DHT production
  • Helps protect hair follicles from damage
  • Helps restore hair density and promotes existing hair growth

Ingredient Information

  • Pumpkin Seed Extract (Cucurbita pepo Seed Extract) – 500mg
  • Beta-Sitosterol (40%) – 325mg
  • Grape Seed Extract (Vitis vinifera Seed Extract Standardized to 95% Proanthocyanidins) - 150mg
  • Green Tea Extract (Camellia sinensis Leaf Extract Standardized to 95% Polyphenols & 48% EGCG) – 62.4mg
  • Zinc Citrate – 56.6mg
  • Vitashine™ as Cholecalciferol from Lichen - 6mg
Androgenic alopecia (AGA), also known as male pattern baldness or female pattern hair loss, is the most common form of hair loss that occurs in both men and women. Genetic factors and excess androgen hormone are the two main causes of AGA (1).

Dihydrotestosterone (DHT) is a potent androgen hormone that plays a significant role in the development and regulation of male characteristics. It is derived from testosterone through the action of the enzyme 5-alpha reductase. While DHT is primarily associated with males, it is also present in females, albeit in smaller amounts (2).

DHT is involved in the development of male genitalia during fetal growth, the deepening of the voice during puberty, and the growth of facial and body hair. However, DHT's effects are not limited to these areas. It also has a significant impact on the hair follicles (2).

DHT has a strong affinity for androgen receptors in the scalp, specifically those located in hair follicles. DHT can have detrimental effects on hair follicles, especially in individuals genetically predisposed to hair loss (3).

DHT can bind to androgen receptors on the hair follicles, causing them to shrink and enter a state of miniaturization. This process is known as androgenetic alopecia or male/female pattern baldness. Over time, the affected hair becomes thinner, shorter, and eventually stops growing altogether, leading to visible hair loss (3).

Given DHT's role in hair loss, many hair restoration approaches focus on inhibiting its production or reducing its activity. DHT blockers, such as medications or natural supplements, work by interfering with the conversion of testosterone to DHT or by arresting DHT from binding to androgen receptors. These interventions aim to halt or slow down the miniaturization process, promoting healthier hair growth and potentially preventing further hair loss.

References:

1. Cho, Y. H., Lee, S. Y., Jeong, D. W., Choi, E. J., Kim, Y. J., Lee, J. G., ... & Cha, H. S. (2014). Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evidence-based complementary and alternative medicine, 2014.

2. Kinter, K. J., & Anekar, A. A. (2022). Biochemistry, dihydrotestosterone. In StatPearls [Internet]. StatPearls Publishing.

3. Ustuner E. T. (2013). Cause of androgenic alopecia: crux of the matter. Plastic and reconstructive surgery. Global open, 1(7), e64.

Hair follicles undergo a cyclic process of growth, rest, and shedding. Excess DHT shortens the growth cycle. Over time, it results in thinner, weaker hair that eventually ceases to grow, leading to visible hair loss.

In men, it typically starts with a receding hairline and thinning at the crown, eventually progressing to partial or complete baldness. Women, on the other hand, typically experience diffuse hair thinning across the top of the scalp.

Unived’s DHT blocker not only targets DHT but also contains nutrients and antioxidants that nourish the hair follicles. These ingredients help strengthen the follicles, improve circulation to the scalp, and support the growth of thick, healthy hair.

Beta-sitosterol: Beta-sitosterol has been found to inhibit the activity of the enzyme 5-alpha reductase, which is responsible for converting testosterone into dihydrotestosterone (DHT) which helps to limit the production of DHT in the body (1).

Pumpkin seed extract: Pumpkin seed extract contains phytosterols, including delta-7-sterols, which have been found to effectively inhibit the enzyme 5-alpha reductase which in turn reduces DHT levels (2).

Zinc: Zinc has been shown to inhibit the activity of the enzyme 5-alpha reductase. Therefore it helps to limit the production of DHT in the body. Zinc deficiency is associated with hair loss and shedding (3).

Green tea extract: Green tea is rich in antioxidants. The polyphenol (EGCG) present in green tea has shown the potential to inhibit the 5-alpha reductase enzyme in laboratory studies. Green tea has anti-inflammatory properties (4).

Vitamin D: Research has shown that individuals with androgenic alopecia, a form of hair loss characterized by progressive thinning, often exhibit low levels of vitamin D in their bloodstream. Vitamin D plays a significant role in the differentiation of keratinocytes and the establishment of a healthy hair growth cycle. In fact, hair follicles are known to have a high concentration of vitamin D receptors, suggesting that a deficiency in this vitamin may impact hair growth (5).

Grape Seed Extract (proanthocyanidins): Grape seed extract is rich in antioxidants. By reducing oxidative stress, grape seed extract may support a healthier scalp environment for hair growth (6).

Some studies suggest that grape seed extract may help improve blood circulation. Better blood flow to the scalp ensures the delivery of nutrients and oxygen to the hair follicles, which are crucial for optimal hair growth and health (6).

References:

1. Zamani, P., Mokhtari, O., & Dehghanian, F. (2021). Identification of beta-sitosterol and stigmasterol as possible inhibitors of 5 alpha-reductase 1: an in-silico study. Precision Medicine and Clinical OMICS, 1(1).

2. Cho, Y. H., Lee, S. Y., Jeong, D. W., Choi, E. J., Kim, Y. J., Lee, J. G., ... & Cha, H. S. (2014). Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evidence-based complementary and alternative medicine, 2014.

3. Kil, M. S., Kim, C. W., & Kim, S. S. (2013). Analysis of serum zinc and copper concentrations in hair loss. Annals of dermatology, 25(4), 405–409.

4. Kwon, O. S., Han, J. H., Yoo, H. G., Chung, J. H., Cho, K. H., Eun, H. C., & Kim, K. H. (2007). Human hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG). Phytomedicine, 14(7-8), 551-555.

5. Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., & Tosti, A. (2019). The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatology and therapy, 9(1), 51–70.

6. Dhariwala, M. Y., & Ravikumar, P. (2019). An overview of herbal alternatives in androgenetic alopecia. Journal of cosmetic dermatology, 18(4), 966-975.

Most DHT blockers contain Biotin, but your’s does’t. Why?

It's important to note that each supplement is designed with specific goals and mechanisms. While biotin is beneficial for overall hair health, it does not directly impact DHT levels or its production. As a result, for this specific DHT blocker formulation, we have chosen to focus on ingredients that target DHT and its effects on hair follicles. If you are interested in incorporating biotin into your hair care routine, we offer Hair Essentials product. It is a separate product designed to support overall hair health

How soon can I start seeing results?

Results can vary depending on the individual. While some people may notice improvements within a few weeks, it typically takes several months of consistent use to see noticeable changes in hair growth and thickness. We recommend using the product daily for a period of three months.

Can DHT blockers be used by women?

DHT blocker is formulated for men due to their connection to male pattern baldness. However, some women may also experience hair loss related to DHT, or other issues which are related to excess DHT and they may benefit from using DHT blockers.

Does a DHT blocker work for all types of hair loss?

DHT blocker is most effective for hair loss related to dihydrotestosterone.

Customer Reviews

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K
Kartik Pal
Suggestion to add Saw Palmetto.

All these botanical ingredients are a natural substitute for Finasteride without having any adverse sexual side effects.
I request you to add another ingredient-Saw Palmetto in this research backed awesome product.

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DHT Blocker

DHT Blocker

Regular price
₹850.00
Sale price
₹850.00
Regular price
Sold out
Unit price
per 
FME.3.4
20.Feb.2024
20.Feb.2025

SUGGESTED USE

Adults take 1 capsule post lunch & 1 capsule post dinner daily, with a glass of water.